Triparna Sen PhD, MS, BS

Cancer Researcher I Inventor I Mentor I Advocate for equal opportunity for women in STEM

New York, NY

1

Office Hours

How does this work?
About

I am a cancer researcher with extensive experience in translational and basic research in the field of immuno-oncology, DNA damage response and drug development. A broad laboratory background has given me a unique perspective on integration of basic discovery research with rapid translation of novel therapies into the clinic. I am currently an Assistant Attending in the Thoracic Oncology Services at Memorial Sloan Kettering Cancer Center, New York, with a joint appointment at Weil Cornell School of Medicine as an Assistant Professor. I have built a preclinical platform to discover therapeutic strategies to reactivate anti-tumor immunity in patients with lung cancer. The overarching goal of my work is to translate new mechanism-driven insights of cancer biology and immuno-oncology into bringing novel therapies to the clinic. My previous research has demonstrated DNA damage response pathways as critical vulnerabilities in small cell lung cancer. Using high-throughput proteomic and genomic analyses, I additionally identified biomarkers of resistance to chemotherapy and targeted therapies in lung cancer. My recent work has demonstrated the crosstalk between replication stress response and antitumor immunity. My contributions have led to multiple high-impact publications and has been recognized with multiple fellowships and awards including the Lung Cancer Research Foundation fellowship (2017), Jeffrey Lee Cousins Fellowship in Lung Cancer Research (2015 to 2018), AACR Women in Cancer Research Scholar Award (2015) and Immuno-oncology Young Investigator Award (2018).

Ask me about
Lung and Thoracic Cancers
immunology
DNA damage
Oncology
Biomarkers
immunotherapy
epigenetic drugs
drug resistance
chemotherapy
Work experience

Apr 2019 - Present

Memorial Sloan Kettering Cancer Center

Assistant Attending

Jan 2014 - Present

Biomedical Journals

Editorial and Review Activities

Editor/Service on Editorial Board(s) 2015-Present Consulting Editor, Onco Targets and therapy, Metalloproteinases in Medicine. Journal Reviewer 2016-Present Molecular Cancer Therapeutics 2014-Present Onco Targets and therapy 2014-Present Metalloproteinases in Medicine 2014-Present Pharmacogenomics and Personalized Medicine 2014-Present Cancer Management and Research

logo

Sep 2018 - Apr 2019

MD Anderson Cancer Center

Instructor

Identifying novel therapeutic strategies for the treatment of lung cancer.

logo

Sep 2014 - Aug 2018

MD Anderson Cancer Center

Postdoctoral Fellow

- Focused on the application of genomic and proteomic platforms for studying signal transduction pathways in lung cancer. - Involved in identifying effective preclinical targets for small cell lung cancer. - Focused in an overall programmatic effort to bring new drugs to the clinic for small cell lung cancer patients and to address important clinical issues, including drug resistance.

Jan 2012 - Jan 2013

Indian Institute of Chemical Biology

Research Associate

Research Associate •Research Focus: Stearylamine bearing cationic liposome formulations as an effective treatment strategy against cancer, targeting the surface- exposed phosphatidylserine. •Formulated and prepared cationic liposomes •Devised effective targeting and delivery strategy of these nanoparticles into the cancer cells. •Patented the liposomal formulation, its mode of action and delivery mechanism

Dec 2005 - Jan 2012

Chittaranjan National Cancer Institute

Doctoral Scholar

Doctoral Scholar •Thesis title: Studies on epigallocatechin-3-gallate (green tea polyphenol) as potential inhibitor of gelatinase-A (MMP-2) and gelatinase-B (MMP-9) and its mechanism of action. •Elucidated the cell-extracellular matrix ligand interactions and its effect in human cancer •Elucidated the different genes upregulated in malignant breast, prostate and ovarian cancer •Studied the mechanism and contribution of epithelial mesenchymal transition in cancer metastsis •Developed transgenic and knockout mouse model

Education

2006 - 2011

Jadavpur University

PhD, Cancer Biology

2003 - 2005

University of Calcutta

Master's Degree, Genetics

2000 - 2003

University of Calcutta

Bachelor's Degree, Physiology

Talk to Triparna

@ Copyright 2020 OfficeHours Technologies Co.