Dr Andrew Gvozdanovic

Neurosurgical Clinical Fellow @NHNN | Honorary Research Fellow @UCL | Digital Health

London, GB

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About

Interested in translational research approaches for the integration of novel digital tools to improve patient HRQoL and operational outcomes. I am an experienced medical doctor with a demonstrated history of working in the NHS and digital health industry. Currently working as a neurosurgical clinical research fellow at the National Hospital for Neurology and Neurosurgery. I graduated from UCL with a degree in Medicine and Surgery as well as an intercalated bachelor's degree in Neuroscience. I have a strong interest in the application of data in predictive analytics and digital biomarkers through the use of ML/AI. Experienced in the applied use of technology in clinical quality improvement. Interested in real world data and evidence as well as organisational logistics.

Ask me about
Digital health
mhealth
Mobile health
remote patient monitoring
patient recorded outcomes
PROMs
ePROs
ePROMs
digital biomarkers
predictive analytics
healthcare
medicine
surgery
perioperative
rpm
real world data
real world evidence
rwd
rwe
clinical research
translational research
medical Research
Remote monitoring
Neurology
neurosurgery
hospital medicine
neuroscience
Work experience

Aug 2020 - Present

University College London Hospitals NHS Foundation Trust

Neurosurgical Clinical Fellow

Aug 2020 - Present

UCL

Honorary Research Fellow

My main focus is the use of novel digital support tools in the care of neuro oncology patients undergoing neurosurgical management. I am particularly interested in the impact these tools can have on clinical outcomes and the holistic patient experience. Heavily focused on both patient and healthcare provider satisfaction in oncological care. Exploring how accessible technologies can improve efficacy of clinical care and efficiency of healthcare systems.

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Nov 2019 - Aug 2020

Huma

Clinical Manager

Huma is a leading health tech start-up with over $50 million fundraised and partnerships with Apple, Tencent, J&J and Bayer. The Huma application allows for remote patient monitoring and the facilitation of real-world data generation to support real world evidence studies. Huma are developing digital biomarkers as ways to utilise data for predictive analytics in healthcare. - Clinical lead for a country wide government backed deployment of the Huma remote patient monitoring solution. Contributed to the development of an integrated digital care pathway. - Joint clinical lead for our COVID-19 remote patient monitoring deployment in partnership with the UK Department of Health. This was the fastest implementation of a digital service in NHS history. - In partnership with a large life sciences company, developed a new digital health solution for pulmonary hypertension. Worked as a clinical product manager to meet key milestones, navigate the regulatory landscape and develop a RWE study concept for the validation of a novel digital tool. Led the design of an operating model for implementation and worked with KOLs to generate a consumer ready product. - Led the concept development of a multifunctional, disease agnostic digital biomarker. Designed a clinical validation study for the digital tool approved by the UK REC. Developed a number of detailed technical and regulatory documents for an MHRA research project and device classification certification.

Aug 2018 - Aug 2019

Cambridge University Hospitals NHS Foundation Trust

Doctor

Rotation 1: Neurosurgery - 4 months SHO level mixed ward and surgical based job. Managed chronic and acutely unwell neurosurgical patients (i.e HCP, SDH, SAH, CE, Ca, HypoNa). Developed clinical skills: accessing EVDs, intrathecal antibiotic administration, lumbar punctures, insertion of lumbar drains, pressure studies via shunt and LP, SDD removal, and insertion of triple bolts. Assisted in a number of surgical procedures such as washout of subdurals, craniotomies, and lumbar decompression. Rotation 2: ENT - 4 months Worked on the ward, in theatre and in A&E to assess and manage a variety of ENT patients. Developed clinical skills in nasal packing, flexible nasendoscopy, peritonsillar abscess drainage, microsuction, and suturing. Managed a number of acute ENT conditions such as post-tonsillectomy bleed, epiglottitis, inhaled foreign bodies, and nose bleeds. Rotation 3: Neurocritical Care - 4 months Worked in a large neurointensive care unit where I became familiar with the management of severely unwell neurosurgical and neurology patients, as well as an element of trauma management. Became familiar with the use of anaesthetic, inotropic, and chronotropic agents used in their care. Developed an understanding of the levels of ICP care. Expanded my understanding of neuroimaging. Clinical skills: insertion of central lines, arterial lines, and bronchoscopy exposure.

Jul 2017 - Jul 2018

Guy's and St Thomas'​ NHS Foundation Trust

Doctor

Rotation 1: Geriatrics - 4 months Worked as part of a multidisciplinary team managing complex patients with high levels of biopsychosocial care needs. Allowed for my development of strong time management skills ensuring timely physical health treatment, and co-ordination of administrative tasks and discharge planning. Rotation 2: Acute Medicine - 4 months Worked on a front line facing post requiring time focused, efficient and concise data gathering of health care needs with risk assessment. Developed management planning skills and carried out further investigations as appropriate in an acute care setting. Rotation 3: Psychiatry - 4 months Worked on an acute inpatient ward with patients of challenging communication skills. The post required a multidisciplinary approach which continued to build upon qualities developed throughout the year. The role required frequent risk assessment, working with information of varying quality and reliability to establish optimisation of ongoing care.

Oct 2015 - Mar 2017

University College London Hospitals NHS Foundation Trust

Honorary Research Fellow

Creation of a prognostic scoring tool for pancreatic neuroendocrine tumours (pNETs) Supervisor: Dr. C. Toumpanakis As part of a team, we reviewed the data of over 200 patients with pancreatic neuroendocrine tumours. Data was used to analyse the impact of a number of clinical, radiological and biochemical factors on prognosis at the time of diagnosis. The aim of this work was to develop a prognostic scoring tool to be used in patients with pNETs. The findings of this research has since been presented at The European Neuroendocrine Tumor Society (ENETS) 2017 conference and will be presented at Digestive Disease Week (DDW) 2017 conference. Predictive Factors for Survival in a Large Cohort of Patients with Pancreatic Neuroendocrine Tumors. Koffas A, Demetriou G, Gvozdanovic A, Brooks P R, Horan C J, Laskaratos F M, Garcia-Hernandez J, Mullan M, Papadopoulou A, Grant L, Mandair D, Caplin M, Toumpanakis C. http://www.gastrojournal.org/article/S0016-5085(17)32368-5/pdf Predictive factors for survival in patients with pancreatic neuroendocrine tumours. Poster presentation, 14th Annual ENETS Conference, Barcelona, Spain, March 2017 Koffas A, Demetriou G, Gvozdanovic A, Brooks P R, Horan C J, Laskaratos F M, Garcia-Hernandez J, Mullan M, Papadopoulou A, Grant L, Mandair D, Caplin M, Toumpanakis C. Epidemiological factors at diagnosis in a large cohort of patients with pancreatic neuroendocrine tumours. Poster presentation, 14th Annual ENETS Conference, Barcelona, Spain, March 2017 Koffas A, Demetriou G, Gvozdanovic A, Brooks P R, Horan C J, Laskaratos F M, Garcia-Hernandez J, Mullan M, Papadopoulou A, Grant L, Mandair D, Caplin M, Toumpanakis C.

Oct 2013 - May 2014

University College London

Undergraduate Researcher

Protection against seizure induced cell death by targeting the Nrf2 pathway Supervisors: Dr. M. Walker, Dr. S. Kovak and Dr. M. Cano Investigated the role of NADPH oxidase activation in the regulation of certain NOX2 subunits. Further to this, investigated the degree to which inducers of an Nrf2 pathway, could have a protective role in seizure induced cell death. Required the use of software such as Volocity 3D Imaging Analysis (Perkin-Elmer for Macintosh), SPSS Statistics and Microsoft Excel. http://www.ucl.ac.uk/ion/departments/epilepsy

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Jun 2010 - Sep 2010

University of Cambridge

Nuffield STEM Bursary Award Researcher

The development of gill arches in Squalus acanthias Baker Lab, Department of Physiology, Development and Neuroscience, University of Cambridge Supervisors: Dr. C. Baker and Dr. A Gillis Assisted in characterising, for the first time, the development of the gill skeleton in an embryonic series of an as-yet unstudied species of shark. Presented my findings at the Nuffield Foundation presentation evening to other receivers of the STEM bursary and representatives from the foundation. http://www.pdn.cam.ac.uk/staff/baker/index.shtml

Education

2011 - 2017

UCL

MBBS, Medicine and Surgery

6 years with intercalation

2011 - 2014

UCL

iBSc (Hons), Neuroscience

Intercalated degree in medical science with neuroscience

Board Certified

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